Walter Sisulu University Departments, the information provided below are all the various campuses with their departments as well as the courses offered
| NMD Campus-Mthatha Campus | Queenstown Campus |
| Zamukulungisa Site-Mthatha | Chiselhust-Buffalo City |
| Ibika-Butterworth Campus | College Street-Buffalo City |
| Cambridge Street-Buffalo City | Potsdam-Buffalo City |